Overview
History of Program
Research Team
Research Programs
Core Facilities
Publications
Funding
Links
Seminars & Meetings

Publications

PUBLICATIONS 2000-2005

Itzhak Fischer, Ph.D.

Ma D, Nothias F, Fischer I. Regulation of the expression and phosphorylation of MAP1B during regeneration of adult DRG neurons. Neuroscience 2000:99:157-170.

Chow SY, Moul J, Tobias C, Himes BT, Liu Y, Obrocka M, Hodge L, Tessler A, Fischer I. 2000. Characterization of multipotential stem cells from embryonic spinal cord in vitro and following intraspinal grafting Brain Res. 2000:874:87-106.

Tobias CA, Kim D, Fischer I. Improved recombinant retroviral titers utilizing trichostatin A BioTechniques, 2000: 29:884-89.

Han S, Fischer I. Neural stem cells and gene therapy: Prospects for repairing the injured spinal cord. JAMA 2000:293:2300-2301.

Fischer I. Candidate cells for transplantation into the injured CNS. In "Progress in Brain Research, Neural Plasticity and Regeneration", Vol. 128, F.J. Seil (ed.), 2000:pp. 253-257.

Gordon-Weeks PR, Fischer I. MAP1B expression and microtubule stabilit in growing and regenerating axons. Microscopy Res & Tech 2000: 48:63-74.

Hormigo A, McCarthy M, Nothias JM, Hasegawa K, Huang W, Friendlander DR, Fischer I, Fishell G, Grumet M. Radial glial cell line C6-R integrates preferentially in adult white matter and facilitates migration of co-implanted neurons in vivo. Exp. Neurol. 2001:168:310-322.

Fischer I, Liu Y. Gene Therapy strategies. In Axonal Regeneration in the Central Nervous System. Ingoglia N and Murray M (eds). Marcel and Dekker. Pp. 2001:563-601.

Ma D, Himes T, Shea T, Fischer I. Axonal transport of microtubule associated protein 1B (MAP1B) in sciatic nerve of adult rats: Distinct transport rates for different isoforms. J. Neurosci. 2000:20:2112-2120.

Jin Y, Tessler A, Fischer I, Houle JD. Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons. Neurorehabilitation and Neural Repair 2001:14: 311-317.

Deng W, Obrocka M, Fischer I, Prockop D. In vitro differentiation of human stromal cells into neuron-like cells by conditions that increase intracellular cyclic AMP. Biol. Biophy. Res Comm. 2001:282:148-152

Tobias CA, Dhoot NO, Wheatley MA, Tessler A, Murray M, Fischer I. Grafting of encapsulated BDNF-producing fibroblasts into injured spinal cord without immune suppression in adult rats. J. Neurotrauma 2001:18:287-301.

Mujtaba T, Han SSW, Fischer I, Sandgren EP, Rao MS. Stable expression of the alkaline phosphatase marker gene by neural cells in culture and after transplantation into the CNS using cells derived from a transgenic rat. Exp. Neurol. 2002:174:48-57.

Wu YY, Mujtaba T, Han SSW, Fischer I, Rao MS. Isolation of a glial-restricted tripotential cell line from embryonic spinal cord cultures. Glia 2002:38:65-79.

Han SSW, Kang D, Mujtaba T, Rao MS, Fischer I. Grafted lineage-restricted neuronal precursors generate mature neurons in the adult spinal cord. Exp Neurol 2002:177:360-375.

Jin Y, Fischer I, Tessler A, Houle JD. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Exp Neurol 2002:177:265-275.

Soares S, VonBoxberg Y, Lombard MC, Ravaille-Veron M, Fischer I, Eyer J, Nothias F. Phosphorylated MAP1B is induced in central sprouting of primary afferents in response to peripheral injury but not in response to rhizotomy. Eur. J. Neurosci 2002: 16:593-606.

Tobias CA, Shumsky JS, Shibata M, Tuszynski MH, Fischer I, Tessler A, Murray M. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy and provides limited regeneration. Exp Neurol 2003:184:97-113.

Emery DL, Royo NC, Fischer I, Saatman KE, McIntosh TK. 2003. Plasticity following injury to the adult central nervous system: Is recapitulation of a developmental state worth promoting? J Neurotrauma 2003: 20:1271-1292.

Mitsui T, Fischer I, Murray M. 2003. Transplants of fibroblasts expressing BDNF and NT3 promote recovery of bladder function following spinal contusion injury in rats. Exp Neurol 2005:194:410-431.

Murray M, Fischer I, Smeraski C, Tessler A, Giszter S. Towards a definition of recovery of function. J Neurotrauma 2004:21:405-413.

Han SS, Liu Y, Tyler-Polsz C, Rao MS, Fischer I. Transplantation of glial-restricted precursor cells into the adult spinal cord: Survival, glial-specific differentiation, and preferential migration in white matter. Glia 2004:45:1-16.

Lepore AC, Han SSW, Tyler-Polsz CJ, Cai J, Rao MS, Fischer I. Differential fate of multipotent and lineage-restrictedneural precursors following transplantation into the adult CNS. Neuron Glia Biology 2004:1:113-126.

Dhoot NO, Tobias CA, Fischer I, Wheatley MA. Peptide-modified alginate surfaces as a growth permissive substrate for neurite outgrowth. J. Biomed Materials Res 2004:71:191-200.

Bakshi A, Fisher O, Dagci T, Himes BT, Fischer I, Lowman A. Mechanically engineered hydrogel scaffolds can promote axonal growth and angiogenesis after transplantation in spinal cord injury. J. Nurosurgery 2004:3:322-329.

Bakshi A, Hunter C, Swanger S, Lepore A, Fischer I. Minimally invasive delivery of stem cells for spinal cord injury: Advantages of the lumbar puncture technique. J. Neurosurgery 2004:3:330-337.

Neuhuber B, Himes BT, Shumsky JS, Gallo G, Fischer I. Neurite growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations. Brain Res 2004:1035:73-85.

Neuhuber B, Gallo G, Howard L, Kostura L, Mackay A, Fischer I. Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: Disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. J Neurosci. Res. 2004:77:192-204.

Liu Y, Han SSW, Wu Y, Tuohy TMF, Xue H, Cai J, Back SA, Sherman LS, Fischer I, Rao MS. CD44 expression identifies astrocyte-restricted precursor cells. Develop. Biol. 2004:276:31-36.

Tobias, C.A.; Han, S.W.; Shumsky, J.S.; Kim, D.; Tumolo, M.; Dhoot, N.O.; Wheatley, M.A.; Fischer, I.; Tessler, A.; Murray, M. Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression. J. Neurotrauma 2005:22:138-156.

Li P, Tessler A, Han SSW, Fischer I, Rao MS, Selzer ME. 2005. Fate of immortalized human neuronal progenitor cells transplanted into rat spinal cord. Arch Neurol 62:223-229.

Tint I, Fischer I, Black M. Acute inactivation of MAP1b in growing sympathetic neurons destabilizes axonal microtubules. Cell Motility and the cytoskeleton 2005:60:48-65.

Mitsui T, Fischer I, Shumsky JS, Murray M. Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder function following spinal contusion injury in rats. Exp. Neurol. 2005:194:410-431.

D K Anderson, M Beattie, A Blesch, J Bresnahan, M Bunge, D Dietrich, V Dietz B Dobkin, J Fawcett, M Fehlings, I Fischer, R Grossman, J Guest, T Hagg, E D Hall, J Houle, N Kleitman, J McDonald, M Murray, A Privat, P Reier, J Steeves, O Steward, W Tetzlaff, M H Tuszynski, S G Waxman, S Whittemore, J Wolpaw, W Young and B Zheng. Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord 2005:43: 453-458.

Lepore A, Fischer I. 2005. Lineage-Restricted Neural Precursors Survive, Migrate and Differentiate Following Transplantation into the Injured Adult Spinal Cord. Exp. Neurol. 2005:194:230-242.

Lepore A, Bakshi A, Swanger SA, Rao MS, Fischer I. 2005. Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain Res. 2005:1045:206-216.

Simon Giszter, Ph.D.

Giszter SF, Kargo WJ. Conserved temporal dynamics and vector superposition of primitives in frog wiping reflexes during spontaneous extensor deletions. Neurocomputing 2000: 32-33:775-783

Giszter SF, Moxon KA, Rybak I, Chapin JK. A neurobiological perspective on design of humanoid robots and their components IEEE Intelligent Systems 2000: 15(4): 64-69

Kargo WJ, Giszter SF. Rapid corrections of animal movements by combinations of force field primitives. J. Neurosci. 2000:20:409-426.

Giszter SF, Loeb E, Mussa-Ivaldi FA, Bizzi E. Dense mapping of frog lumbar spinal cord: organization of force and muscle use. Human Movement Science 2000: 19:597-626.

Giszter, SF, Davies MR, Kargo WJ. Perspective. Augmenting postural primitives in spinal cord: Dynamic force-field structures used in trajectory generation. Ch 25 In: Biomechanics and Neural control of Movement. ed. Winters and Crago. Springer-Verlag, 2000; pp. 334-346.

Giszter SF, Grill W, Lemay M, Mushahwar V, Prochazka A. Intraspinal microstimulation: techniques, perspectives and prospects for FES In: Neural prostheses for restoration of Sensory and motor function. ed. KA Moxon and JK Chapin CRC Press, 2000; pp.

Giszter SF, Kargo WJ. Movement organization in the frog spinal cord: Prerational intelligence? In: Pre-rational intelligence: Adaptive Behavior and Intelligent Systems without Symbols and Logic. Volume 1. Ed. H. Cruse, J Dean, and H Ritter. Studies in Cognitive Systems series. Kluwer Academic Press, 2000; pp. 323-342.

Kargo WJ, Giszter SF. Afferent roles in hindlimb wiping reflex: free limb kinematics and motor patterns. J Neurophysiol 2000:83(3): 1480-1501.

Giszter SF, Kargo WJ. Modeling of dynamic controls in the frog wiping reflex: force field level controls. Neurocomputing 2001: 38-40: 1239-1247.

Giszter SF, Moxon KA, Rybak I, Chapin JK. Neurobiological and neurorobotic approaches to design of a controller for a humanoid motor system. Robotics and Autonomous Systems 2001: 37:219-235.

Giszter SF. Biomechanical primitives and heterarchical control in tetrapod locomotion. In Neurotechnology for biomimetic robots ed Ayers J Rudolph A and Davis J MIT Press, 2001; pp 223-240.

Giszter SF. Quantization of motor drive into time-frequency atoms using independent component analysis and matching pursuit algorithms 2001 Proceedings IEEE/EMBS Istanbul Turkey 2001;

Giszter SF, Kargo WJ. Separation and estimation of muscle spindle and tension receptor populations by vibration of the biceps muscle in the frog. Ital. Archiv. Biol. 2002: 140:283-294.

Giszter SF. (2002) Case Study 4: “How Frogs Groom”Chapter 4, Motor Coordination in artificial Ethology. O Holland, D. McFarland, oxford UP.

Shumsky JS, Tobias CA, Tumolo M, Giszter SF, Murray M. Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function. Exp Neurol 2003:184:114-130.

Maltenfort MG, Markin S, Lemay MA, Giszter SF. Fine control of acceleration and force at the cat’s toe. Engineering in Medicine and Biology Society. Proc of the 25th Ann International Conference of the IEEE, 2003:Vol 2, 17-21:1734-1737.

Giszter SF. Unitary premotor drives and modular reflex primitives in frog spinal cord. Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE ,Volume: 4 , 2003:17-21 Pages:3843 – 3845.

Giszter SF, Hart CB. Expanding a behavioral repertoire by tuning spinal primitives. Neural Engineering, 2003. Conference Proceedings. First International IEEE EMBS Conference 2003: 1: 430 – 433.

Murray M, Fischer I, Smeraski C, Tessler A, Giszter S. Towards a definition of recovery of function. J Neurotrauma 2004:21:405-413.

Hart CB, Giszter SF. Modular premotor drives and unit bursts as primitives foro frog motor behaviors. J Neurosci 2004:24:5269-5282.

Silverman J, Garnett NL, Giszter SF, Heckman CJ 2nd, Kulpa-Eddy JA, Lemay MA, Perry CK, Pinter M. 2005. Decerebrate mammalian preparations: unalleviated or fully alleviated pain? A review and opinion. Contemp Top Lab Anim Sci 44:34-36.

Giszter SF, Hart CB, Udoekwere UI, Markin S, Barbe C. 2005. A real-time system for small animal neurorobotics at spinal or cortical levels. Neural Engineering. Conference Proceedings, 2nd International IEEE EMBS Conference on March 16-19, pgs. 450-453.

B. Timothy Himes, Ph.D.

Ma D, Himes BT, Shea TB, Fischer I. Axonal transport of microtubule-associated protein 1B (MAP1B) in sciatic nerve of adult rat: Distiinct transport rates for different isoforms. J Neurosci 2000:20:2112-2120.

Chow SY, Moul J, Tobias CA, Himes BT, Liu Y, Obrocka M, Hodge L, Tessler A, Fischer I. Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord. Brain Res 2000:874:87-106.

Himes BT, Liu Y. Solowska JM, Snyder EY, Fischer I, Tessler A. Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats. J. Neurosci. Res. 2001:65: 549-564.

Himes BT, Tessler A. Neuroprotection from cell death following axotomy. In N. Ingoglia and M. Murray (eds.) Nerve Regeneration. New York: Marcel Dekker. 2001: Pp. 477-503.

Liu Y, Himes BT, Murray M, Tessler A, Fischer I. Grafts of BDNF-producing fibroblasts that promote regeneration of axotomized rubrospinal neurons also rescue most neurons from retrograde death and prevent their atrophy. Exp. Neurol. 2002:178:150-164.

Schwartz ED, Himes BT. New model of minimally invasive experimental spinal cord injury. Am. J. Neuroradiol. 2003:24(2):166-168.

Bakshi A, Fisher O, Dagci T, Himes BT, Fischer I, Lowman A. Mechanically engineered hydrogel scaffolds for axonal growth and angiogenesis after transplantation in spinal cord injury. J. Neurosurg. Spine 2004:1(3):322-329.

Swanger SA, Neuhuber B, Himes BT, Bakshi A, Fischer I. Analysis of allogeneic and syngeneic bone marrow stromal cell graft survival in the spinal cord. Cell Transplantation 2005:14(10):775-786.

John Houle, Ph.D.

Peterson CA, Murphy RJL, Dupont-Versteegden EE, Houle JD. Cycling exercise and fetal spinal cord transplantation act synergistically on atrophied muscle following chronic spinal cord injury in rats. Neurorehab and Neural Repair 2000:14: 85-91.

Dupont-Versteegden EE, Murphy RJL, Houle JD, Gurley CM, Peterson CA. Mechanisms contributing to restoration of muscle size with exercise and fetal transplants after spinal cord injury. Am. J. Physiol. 2000:279: C1677-C1684.

Jin Y, TesslerA, I. FischerI, Houle JD. Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons. Neurorehabilitation and Neural Repair. 2001:14:311-317.

Houle JD, Jin Y. Chronically injured supraspinal neurons exhibit only modest axonal dieback in response to a cervical hemisection lesion. Exp. Neurol. 2001:167: 208-217.

Gilmore SA, Sims T, Houle JD. Glial boundaries in experimentally manipulated spinal cords, In: Glial Interfaces in the Nervous System - Development and Regeneration, H. Aldskogius and J. Fraher, eds., IOM Press, pp 61-70 2001.

Storer PD, Houle JD, Oblinger MM, Jones KJ. A combination of gonadal steroid treatment and peripheral nerve grafting results in a peripheral motoneuron-like pattern on BII-tubulin mRNA expression in axotomized hamster rubrospinal motoneurons. J. Comp. Neurol. 2002:449: 364-373.

Dupont E.E, Knox M, Gurley CM, Houle JD, Peterson CP. Maintenance of muscle mass is not dependent on the calcineurin/NFAT pathway. Am. J. Physiol. 2002:282: C1387-C1395.

Jin Y, Fischer I, Tessler A. Houle JD. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Exp. Neurol. 2002:177: 265-275.

Houle JD, Tessler A. Repair of chronic spinal cord injury. Exp. Neurol. 2003:182: 247-260.

Gilmore SA, Phillips N, Liu K-M, Houle JD. Radiation-induced modulation of the microglial population in the normal and injured mature spinal cord. Exp. Neurol. 2003:182: 169-179.

Storer PD, Houle JD BII-tubulin and GAP-43 mRNA expression in chronically injured neurons of the red nucleus after a second spinal cord injury. Exp. Neurol. 2003:183: 537-547.

Storer PD, Dolbeare D, Houle JD. Treatment of the chronically injured spinal cord with neurotrophic factors stimulates BII-tubulin and GAP-43 expression in rubrospinal tract neurons. J. Neurosci. Res. 2003:74: 502-511.

Dolbeare D, Houle JD. Glial cell line-derived neurotrophic factor (GDNF) promotes neuroprotection and neurorepair after spinal cord injury. J. Neurotrauma 2003:20: 1251-1261.

Beaumont, E., J.D. Houle, C.A. Peterson and P.F. Gardiner. 2004. Fetal spinal cord transplant and passive exercise help to restore motoneuronal properties after spinal cord transection in rats. Muscle & Nerve 29:234-242.

Dupont-Versteegden, E.E., J.D. Houle, R.A. Dennis, J.-M. Zhang, M. Knox, G. Wagoner and C.A. Peterson. 2004. Exercise-induced gene expression in soleus muscles is dependent on time after spinal cord injury in rats. Muscle & Nerve 29: 73-81.

Michel Lemay, Ph.D.

Lemay MA, Grill WM. Endpoint Force Patterns Evoked by Intraspinal Stimulation - Ipsilateral and Contralateral Responses. Chicago 2000 World Congress on Medical Physics and Biomedical Engineering, 2000.

Lemay MA, Galagan JE, Hogan N, Bizzi E. Modulation and vectorial summation of the spinalized frog's hindlimb end-point forces produced by intraspinal electrical stimulation of the cord," IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol. 9, pp. 12-23, 2001.

Bhowmik M, Tobias CA, Fischer I, Murray M, Lemay MA. Locomotor recovery promoted by sensorimotor training and the graft of fibroblasts genetically engineered to produce BDNF and NT3 in the injured cat spinal cord. 28th Northeast Bioengineering Conference, Philadelphia, 2002.

Scabich JA, Ellis-Davies GCR, Lemay MA, Giszter SF. Testing of photolytic uncaging with intraspinal fiber optics as a basis for motor neuroprostheses. 28th Annual Northeast Bioengineering Conference, Philadelphia, 2002.

Lemay MA, McConnell GC, Kao T, Joyce DM, Grill WM. Endpoint forces obtained during intraspinal microstimulation of the cat lumbar spinal cord - experimental and biomechanical model results. 28th Northeast Bioengineering Conference, Philadelphia, 2002.

Lemay MA, Grill WM. Modularity of motor output evoked by intraspinal microstimulation in cats. J Neurophysiol 2004:91: 502-514.

Burns AS, Lemay MA, Tessler A. Spontaneous potentials in animal models of spinal cord injury. Muscle and Nerve 2005:31:46-51.

Marion Murray, Ph.D.

Liu Y, Murray M, Tessler A, Fischer I. Grafting of genetically modified fibroblasts into the injured spinal cord. Prog Br Res 2000: 128:309-319.

Shibata M, Murray M, Tessler A, Ljubetic C, Connors T, Saavedra RA. Single injections of a DNA plasmid that contains the hujman Bcl-2 gene prevent loss and atrophy of distinct neuronal populations after spinal cord injury in adults rats. Neurorehab.Neural Repair. 2000: 14: 321-332.

Saavedra RA, Murray M., deLacalle S. Tessler A. In vivo neuroprotection of injured CNS neurons by a single injection of a DNA plasmid encoding the BCL-2 gene. Progress in Brain Research. In Seil FJ (ed) Progress in Brain Research, Neural Plasticity and Regeneration. 2000: 128365-372. Elsevier Science.

Kim D, Murray, M, Simansky, KJ. The serotonergic 5-HT2C agonist m-chlorophenylpiperazine increases weight supported locomotion without development of tolerance in rats with spinal transections. Exp Neurol 2001: 169:496-500.

Murray M, Fischer I. Transplantation and gene therapy: Combined approaches for repair of spinal cord injury. Neuroscientist 2001:7:28-41.

Tobias CA, Dhoot NO, Wheatley RA, Tessler A, Murray M, Fischer I. Grafting of encapsulated BDNF-producing fibroblasts into the injured spinal cord without immune suppression in adult rats. J. Neurotrauma 2001:18: 287-301.

Murray M, Kim D, Liu Y, Tobias C, Tessler A, Fischer I. Transplantation of genetically modified cells contributes to repair and recovery from spinal injury. Brain Res. Reviews. 2002:40:292-300.

Schwartz, ED, Shumsky JS, Wehrli S, Tessler A, Murray M, Hackney DB. Ex vivo MR apparent diffusion coefficients correlate with motor recovery mediated by intraspinal transplants of fibroblasts genetically modified to express BDNF. Exp. Neurol. 2003:182:49-63.

Murray M, Tobias CA. Regeneration and sprouting in the injured spinal cord. Topics in Spinal Cord Injury Rehabilitation 2003:8:37-51

Shumsky JS. Tobias CA, Tumolo M, Giszter SF, Murray M. Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function. Exp Neurol 2003:184:114-130.

Murray M, Tobias CA. Regeneration and sprouting in the injured spinal cord. Topics in Spinal Cord Injury Rehabilitation 2003:8:37-51.

Murray M, Fischer I, Smeraski C, Tessler A, Giszter SF. How do we define recovery of function. J Neurotrauma 2004:21:405-413.

Murray M, 2004. Cellular transplants: steps toward restoration of function in spinal injured animals. Progress in Brain Research. 2004:143:133-146

Murray M. 2004. Molecular mechanisms of axonal regeneration in the central nervous system. Advanced Studies in Medicine 2004:4:S335-338.

LCME Accrediation Letter 10-15-2005.pdf(85KB)

Nothias J-M, Mitsui T, Shumsky JS, Fischer I, Murray M. Combined effects of neurotrophin secreting transplants, exercise and serotonergic drug challenge improve function in spinal rats. Neurorehab.Neural Repair 2005:19:1-16.

Mitsui T, Fischer I, Shumsky JS, Murray M. 2005. Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats. Exp Neurol 194:410-431.

Hayashi Y, Shumsky JS, Connors T, Otsuka T, Fischer I, Tessler A, Murray M. Immunosuppression with either cyclosporine A or FK506 promotes repair processes after spinal cord injury. J. Neurotrauma. 2005:22:1267-1281.

Mitsui T, Shumsky JS, Lepore A, Murray M, Fischer I. Transplantation of neural and glial restricted precursors into contused spinal cord improves bladder and motor functions, decreases allodynia and modified intraspinal circuitry. J. Neuroscience 2005:25:9624-9636.

Schwartz ED, Chin C.-L, Shumsky JS. Jawad AF, Brown BK, Wehrli S, Tessler A, Murray M, Hackney DB. Apparent diffusion coefficients within spinal cord transplants and surroundling whit matter correlate with axonal dieback following injury. Am. J. Neuroradiol. 2005:26:7-18.

Shumsky JS, Kao T, Amato N, Simansky K, Murray M, Moxon KA. Partial 5-HT1A receptor agonist activity by the 5-HT2C receptor antagonist SB 206,553 is revealed in rats spinalized as neonates. Exp Neurol. 2005:191:361-365

Birgit Neuhuber, Ph.D.

Neuhuber B, Gallo G, Howard L, Kostura L, Mackay A, Fischer I. 2004. Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: Disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. J. Neurosci. Res. 2004:77(2): 192-204.

Swanger SA, Neuhuber B, Himes BT, A. Bakshi A, Fischer I. Improving graft survival of bone marrow stromal cells in the CNS. Cell Transplantation 2005:14(10):775-786.

Neuhuber B, Himes BT, Shumsky JS, Gallo G, Fischer I. Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations. Brain Res 2005:1035: 73-85.

Bakshi A, Barshinger AL, Swanger SA, Madhavani V, Shumsky JS, Neuhuber B, Fischer I. Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: A novel method for minimally invasive cell transplantation. J. Neurotrauma 2006:23(1):55-65.

Ramesh Raghupathi, Ph.D.

Raghupathi R, Graham DI, McIntosh TK. Apoptosis after traumatic brain injury. J. Neurotrauma 2000: 17: 927-938.

Duhaime AC, Margulies SS, Durham SR, O’Rourke MM, Golden JA, Marwaha S, Raghupathi R. Maturation-dependent response of the piglet brain to scaled cortical impact. J. Neurosurg. 2000: 93:455-462.

Graham DI, Raghupathi R, Saatman KE. Meaney D, McIntosh TK. Tissue tears in the white matter after lateral fluid-percussion brain injury in the rat: relevance to human head injury. Acta Neuropathol. 2000: 99:117-124, 2000.

O’Dell DM, Raghupathi R, Crino PB, Eberwine JH, McIntosh TK. Traumatic brain injury alters the molecular fingerprint of TUNEL-positive, cortical neurons in vivo : a single cell analysis. J.Neurosci. 2000: 20:4821-4828.

Emery DL, Raghupathi R, Saatman KE, Fischer I, McIntosh TK. Alteration in growth-related proteins following experimental brain injury: a temporary increase in regenerative potential occurs after brain trauma. J. Comp. Neurol., 2000:424(3):521-531.

Smith FA, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Meaney DF, Graham DI. TUNEL-positive staining of surface contusions after fatal head injury in man. Acta Neuropathol. 2000: 100:537-545.

Bareyre FM, Raghupathi R, Saatman KE, McIntosh TK. DNase-I disinhibition is predominantly associated with actin hyperpolymerization after traumatic brain injury. J. Neurochem. 2001: 77:173-181.

Bain AC, Raghupathi R, Meaney DF. Dynamic stretch correlates to both morphological abnormalities and electrophysiological impairment in a model of traumatic axonal injury. J. Neurotrauma 2001: 18:499-511.

Williams S, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Graham DI. In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man. Acta Neuropathol 2001: 102:581-590.

Raghupathi R, Conti AC, Graham DI, Krajewski S, Reed JC, Grady MS, McIntosh TK. Mild traumatic brain injury induces apoptotic cell death in the cortex that is preceded by decreases in Bcl-2 immunoreactivity. Neuroscience 2002:110:605-616.

Raghupathi R. Margulies, SS. Traumatic axonal injury following closed head injury in the neonatal pig. J.Neurotrauma 2002: 19:843-853.

Huh J, Laurer HL, Raghupathi R, Helfaer MH, Saatman KE. Rapid loss and partial recovery of neurofilament immunostaining following focal brain injury in mice. Exp Neurol. 2002: 175:198-208.

Raghupathi R, Strauss KI, Zhang C, Krajewski S, Reed JC, McIntosh TK. Temporal alterations in cellular Bax:Bcl-2 ratio following traumatic brain injury in the rat. J. Neurotrauma 2003:20:421-435.

Thompson HJ, Tkacs NC, Saatman KE, Ragupathi R, McIntosh TK. Hyperthermia following traumatic brain injury: a critical evaluation. Neurobiol Dis 2003:12:163-173.

Huh JW, Raghupathi R, Laurer HL, Helfaer MA, Saatman KE. Transient loss of microtubule-associated protein 2 immunoreactivity after moderate brain injury in mice. J Neurotrauma 2003:20:975-984.

Raghupathi R, Mehr M, Helfaer MA, Margulies SS. 2004. Traumatic axonal injury is exacerbated following repetitive closed head injury in the neonatal pig. J. Neurotrauma 21:307-316.

Wilson S, Raghupathi R, Saatman KE, Mackinnon M.-A, McIntosh TK, Graham DI. 2004. Continued in situ DNA fragmentation of microglia/macrophages in white matter weeks and months after traumatic brain injury. J. Neurotrauma 2004:21:239-250.

Otori T, Friedland JC, Sinson G, McIntosh TK, Raghupathi R, Welsh FA. Traumatic brain injury elevates glycogen and induces tolerance to ischemia in rat brain. J. Neurotrauma 2004:21:707-718.

Marciano PG, Brettschneider J, Manduchi E, Davis JE, Eastman S, Raghupathi R, Saatman KE, Speed TP, Stoeckert CJ, Eberwine JH, McIntosh TK. Neuron-specific mNRA complexity responses during hippocampal apoptosis after traumatic brain injury. J. Neurosci. 2004:24:2866-2876.

Lenzlinger, PM, Saatman KE, Hoover RC, Cheney JA, Bareyre FM, Raghupathi R, Arnold LD, McIntosh TK. Inhibition of vascular endothelial growth factor receptor (VEGFR) signaling by BSF476921 attenuates regional cerebral edema following traumatic brain injury in rats. Restor. Neurol. Neurosci. 2004:22:73-79.

Raghupathi R. Cell death mechanisms following traumatic brain injury. Brain Pathology 2004:14:215-222.

Raghupathi R. Common patterns of Bcl-2 family gene expression in two traumatic brain injury models. Neurotox Res. 2004: 6:333-42.

Longhi L, Saatman KE, Fujimoto S, Raghupathi R, Meaney DF, Davis J, McMillan A, Conte V, Laurer H.L, Stein S, Stocchetti N, McIntosh TK. 2005. Temporal window of vulnerability to repetitive experimental concussive brain injury. Neurosurgery 2005:56:364-74.

Young Jin Son, Ph.D.

Son Y-J, Scranton TW, Sunderland WJ, Baek SJ, Miner JH, Sanes JR, Carlson SS. The synaptic vesicle protein SV2 is complexed with an 5-containing laminin on the nerve terminal surface. J. Biol. Chem 2000: 275(1) : 451-60.

Sunderland WJ, Son Y-J, Miner JH, Sanes JR, Carlson SS. The presynaptic calcium channel is part of a transmembrane complex linking a synaptic laminin (421) with non-erythroid spectrin. J. Neurosci 2000:20(3):1009-19

Nguyen QT, Son Y-J, Sanes JR, Lichtman JW. 2000. Nerve terminals form but fail to mature when postsynaptic differentiation is blocked : In vivo analysis using mammalian nerve-muscle chimeras. J. Neurosci. 2000:15:6077-86.

Love FM, Son Y-J, Thompson WJ. Activity alters muscle reinnervation and terminal sprouting by inhibiting the formation of Schwann cell pathways linking synaptic sites. J. Neurobiol. 2003:54:566- 576.

Jed Shumsky, Ph.D.

Tonkiss J, Shultz PL, Shumsky JS, Fiacco TA, Vincitore M, Rosene DL, Galler JR. Chlordiazepoxide-induced learning deficits: Dose-dependent differences following prenatal malnutrition. Pharmacol Biochem Behav 2000: 65: 105-116.

Stanwood GD, Washington RA, Shumsky JD, Levitt P. Prenatal cocaine exposure produces consistent developmental alterations in dopamine-rich regions of the cerebral cortex. Neuroscience 2001:106: 5-14.

Shumsky JS, Wu Y, Murphy EH, Nissanov J, O'Brien-Jenkins A, Grayson DR. Differential effects of prenatal cocaine exposure on selected subunit mrnas of the GABA(a) receptor in rabbit anterior cingulate cortex. J Chem Neuroanat. 2002: 24:243-55.

Schwartz ED, Shumsky JS. Wehrli S, Tessler A, Murray M, Hackney DB. 2003. Ex vivo MR determined apparent diffusion coefficients correlate with motor recovery mediated by intraspinal transplants of fibroblasts genetically modified to secrete BDNF. Exp Neurol 182:49-63.

Tobias CA, Han SW, Shumsky JS, Kim D, Tumolo M. Dhoot NO, Wheatley MA, Fischer I, Tessler A, Murray M. Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression. J. Neurotrauma 2004:22:138-156.

Tobias CA, Han SSW, Shumsky JS, Kim D, Tumulo M, Dhoot NO, Wheatley MA, Fischer I, Tessler A, Murray M. Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression. J. Neurotrauma. 2005:22: 138-156.

Hayashi Y, Shumsky JS, Connors T, Otsuka T, Fischer I, Tessler A, Murray M. 2005. Immunosuppression with either cyclosporine A or FK506 promotes repair processes after spinal cord injury. J. Neurotrauma. 2005:22:1267-1281.

Schwartz ED, Duda J, Shumsky JS, Cooper ET, Gee J. Spinal cord diffusion tensor imaging and fiber tracking can identify white matter tract disruption and glial scar orientation following lateral funiculotomy, J Neurotrauma 2005:22:1388-1398.

Alan Tessler, M.D.

Selzer ME, Tessler A. Spinal cord regeneration. In E.G. Gonzalez, S.J. Myers, J.E. Edelstein, J.S. Lieberman and J.A. Downey (eds.) Downey and Darling’s Physiological Basis of Rehabilitation Medicine. 3rd Edition: Woburn, MA. 2000: Pp. 629-662.

Jin Y, Tessler A, Fischer I, Houle JD. Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons. Neurorehab. Neural Repair 2000:14: 319-330.

Chow SY, Moul J, Tobias CA, B. Himes BT, Liu Y, Obrocka M, Hodge L, Tessler A, Fischer I. Characterization and intraspinal grafting of EGF/bFGF dependent neurospheres derived from embryonic rat spinal cord. Brain Res. 2000:874: 87-106.

Iwakawa M, Mizoi K, Tessler A, Itoh Y. Intraspinal implants of fibrin glue containing glial cell line-derived neurotrophic factor promote dorsal root regeneration into spinal cord. Neurorehab. Neural Repair 2001:15: 173-182.

Himes BT, Liu Y, Solowska JM, Fischer I, Tessler A. Transplants of cells genetically modified to express neurotrophin-3 (NT-3) rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats. J. Neurosci. Res. 2001:65: 549-564.

Kim D, Schallert T, Liu Y, Browarak T, Nayeri N, Tessler A, Fischer I, Murray M. Transplantation of genetically modified fibroblasts expressing BDNF in adult rats with a subtotal hemisection improves some motor functions. Neurorehab. Neural Repair 2001:15: 141-150.

Shibata M, Murray M, Tessler A, Ljubetic C, Saavedra RA. Single injections of a DNA plasmid that contains the human bcl-2 gene prevent loss and atrophy of distinct neuronal populations after spinal cord injury in adult rats. Neurorehab. Neural Repair 2001:14: 321-332.

Murray M, Kim D, Liu Y, Tobias C, Tessler A, Fischer I. Transplantation of genetically modified cells contributes to repair and recovery from spinal injury. Brain Res. Rev. 2002:40: 292-300.

Ditunno JF, Flanders AE, Kirshblum S, Graziani V, Tessler A. Predicting outcome in traumatic spinal cord injury. In: S Kirshblum, DI Campagnolo and JA DeLisa (Eds.) Spinal Cord Medicine. Philadelphia: Lippincott Williams & Wilkins, 2002:pp. 108-122.

Burns AS, Lee BS, Ditunno JF, Tessler A. Patient selection for clinical trials: the reliability of the early spinal cord injury examination. J. Neurotrauma 2003:20 (5): 477-482.

Houle JD, Tessler A. Repair of chronic spinal cord injury. Exp. Neurol. 2003:182: 247-260.

Tobias CA, Shumsky JS, Shibata M, Tuszynski MH, Fischer I, Tessler A, Murray M. Delayed grafting of BDNF and NT-3-expressing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy and provides limited regeneration. Exp. Neurol. 2003:184:97-113.

Ditunno, JF., Little JW, Burns AS, Tessler A. Spinal shock revisited: a four phase model. Spinal Cord 2004:42:383-395.

Murray M, Fischer I, Smeraski C, Tessler A, Giszter S. Towards a definition of recovery of function. J. Neurotrauma 2004:21:405-413.

Burns AS, Lemay MA, Tessler A. Spontaneous potentials in distal muscles in animal models of spinal cord injury. Muscle and Nerve 2005:31:46-51.

Schwartz ED, Chin CL, Shumsky JS, Jawad AF, Brown BK, Wehrli S, Tessler A, Murray M, Hackney DB. Apparent diffusion coefficients in spinal cord transplants and surrounding white matter correlate with degree of axonal dieback after injury in rats. Am. J. Neuroradiol. 2005:26 (1): 7-18.

Schwartz ED, Cooper ET, Chin C-L, Wehrli S, Tessler A, Hackney DB. Ex vivo evaluation of ADC values within spinal cord white matter tracts. Am. J. Neuroradiol. 2005:26 (2): 390-397.

Li P, Tessler A, Han SSW, Fischer I, Rao MS, Selzer ME. Fate of immortalized human neuronal progenitor cells transplanted into rat spinal cord. Arch. Neurol. 2005:62: 223-229.

Anthony S. Burns, M.D.

Burns AS, Dillingham TR. Importance of gadolinium enhancement when using MRI to evaluate spinal cord pathology: case report. Am J Phys Med Rehabil 2000; 79(4):399-403.

Burns AS, Putzke JD, Richards JS, Jackson AB. Gender and its impact on post-acute secondary medical complications following spinal cord injury. Topics in Spinal Cord Injury Rehabilitation 2000; 6(1):66-75.

Burns AS, Jackson AB. Gynecologic and reproductive issues in women with spinal cord injury. Physical Medicine and Rehabilitation Clinics of North America 2001; 12(1):183-199.

Burns AS, Lauder TD. Deep water running: an effective non-weight bearing exercise for the maintenance of land based running performance. Military Medicine 2001; 166 (3):253-258.

Burns AS, Meythaler JM. Intrathecal baclofen in tetraplegia of spinal origin: efficacy for upper extremity hypertonia. Spinal Cord 2001; 39(8):413-9.

Burns AS, Rivas D, Ditunno JF. Neurogenic bladder and sexual dysfunction following spinal cord injury. Spine 2001; 24S:S137-S145.

Burns AS, Ditunno JF. Rehabilitation outcomes in spinal cord injury: evidence-based analysis of neurological and functional recovery. Spine 2001; 24S:S129-S136.

Burns AS, Burchiel K. Summary statement: pain, spasticity, and bladder and sexual function after spinal cord injury. Spine 2001; 24S:S161.

Doherty JG, Burns AS, O’Ferrall DM, Ditunno JF. Prevalence of upper motor neuron versus lower motor neuron lesions in complete lower thoracic and lumbar spinal cord injuries. Journal of Spinal Cord Medicine 2002; 25(4):289-92.

Burns AS, Lee BS, Ditunno JF, Tessler A. Patient selection for clinical trials: the reliability of the early spinal cord injury examination. J Neurotrauma 2003; 20(5): 477-482. (Best Journal Article by an American Spinal Injury Assoc.Member 2004)

Ditunno JF, Apple DF, Burns AS, et al. A view of the future Model Spinal Cord Injury Systems (MSCIS) through the prism of past achievements and current challenges. J Spinal Cord Med 2003 26:110-115.

Ditunno JF, Little JW, Tessler A, Burns AS. Spinal shock revisited: a four phase model. Spinal Cord 2004; 42: 383-395.

Oleson CV, Geisler FH, Coleman WP, Burns AS. Prognostic value of pinprick preservation in motor complete, sensory incomplete spinal cord injury. Arch Phys Med Rehabil 2005; 86(5):988-92. (Foundation for PM&R, 2005 Education Research Fund (ERF) Best Research Paper Award)

Ditunno JF, Burns AS, Marino RJ. Future treatment strategies in spinal cord injury rehabilitation: recovery outcome, mechanisms and measures. Journal of Rehabilitation Research & Development 2005; 42(3):35-42.

Torina PJ, Flanders AE, Carrino JA, Burns AS, Friedman DP, Vacarro AR, Harrop JS. Incidence of vertebral artery thrombosis in cervical spine trauma: correlation with severity of spinal cord injury. Am J Neuroradiol 2005; 26:2645-2651.

Burns AS, Lemay MA, Tessler A. Spontaneous potentials in distal muscles in animal models of spinal cord injury. Muscle and Nerve 2005:31:46-51.

Eric Schwartz, M.D.

Schwartz ED and Hackney DB, Diffusion Weighted MRI and the Evaluation of Spinal Cord Axonal Integrity Following Injury and Treatment. Exp Neurol. 2003 184(2):570-589.

Chin CL, Wehrli FW, Fan Y, Hwang SN, Schwartz ED, Nissanov J and Hackney DB, Assessment of axonal fiber tract architecture in excised rat spinal cord by localized NMR q-space imaging: simulations and experimental studies. MRM Magnetic Resonance in Medicine, 2004 Oct;52(4):733-40.

Schwartz ED, Chin CL, Shumsky JS, Jawad AF, Brown BK, Wehrli S, Tessler A, Murray M, Hackney DB, Apparent diffusion coefficients in spinal cord transplants and surrounding white matter correlate with degree of axonal dieback after injury in rats. AJNR American Journal of Neuroradiology, 2005 Jan;26(1):7-18.

Schwartz ED, Cooper ET, Fan Y, Jawad AF, Chin CL, Nissanov J, Hackney DB. MRI diffusion coefficients in spinal cord correlate with axon morphometry, Neuroreport, 2005 Jan 19;16(1):73-76.

Schwartz ED, Cooper ET, Chin CL, Wehrli S, Tessler A, Hackney DB, Ex vivo evaluation of ADC values within spinal cord white matter tracts. AJNR American Journal of Neuroradiology, 2005 Feb;26(2):390-7.
Schwartz ED, Duda J, Shumsky JS, Cooper ET, Gee J. Spinal cord diffusion tensor imaging and fiber tracking can identify white matter tract disruption and glial scar orientation following lateral funiculotomy. J Neurotrauma 2005 Dec;22(12):1388-98.

Schwartz ED, Duda J, Cooper E, Shumsky JS, Gee JC. Spinal cord diffusion tensor imaging and fiber tracking can identify white matter tract disruption and glial scar orientation following partial hemisection, Proceedings of the American Society of Neuroradiology 43rd Annual Meeting, Toronto, ON 2005.

Editorials, Reviews, Chapters:
Schwartz ED, Chin C-L, Takahashi M, Hwang SN, Hackney DB. Diffusion Weighted Imaging of the Spinal Cord, in Neuroimaging Clinics of North America, (Melhem ER, editor), February 2002, pp 125-146.

Schwartz ED, Book Review: Brain Edema XI, AJNR American Journal of Neuroradiology, 23: 890-891; 2002.

Schwartz ED, Himes BT, Editorial: A new model of minimally invasive experimental spinal cord injury, AJNR American Journal of Neuroradiology, 24:166-8; 2003.

Schwartz ED, Book Review: MR Imaging of the Spine and Spinal Cord AJNR American Journal of Neuroradiology, 25:1452; 2004.

Schwartz ED, Editorial: MRI and the evaluation of the blood-spinal cord barrier following injury, AJNR American Journal of Neuroradiology, 26(7):1609-10; 2005.

PUBLICATIONS FROM 2000 AND BEFORE

Chow SY, Moul J, Tobias C, Himes BT., Liu Y, Obrocka M, Hodge L, Tessler A, Fischer I. (2000) Characterization of multipotential stem cells from embryonic spinal cord in vitro and following intraspinal grafting Brain Res. 874:78-106. Abstract.

Fischer I., Liu Y. (2000) Gene Therapy strategies in CNS axon regeneration. In Nerve Regeneration. Ingoglia N and Murray M (eds). pp. 563-602, Marcel and Dekker.

Giszter SF and Kargo WJ. (2000) Conserved temporal dynamics and vector superposition of primitives in frog wiping reflexes during spontaneous extensor deletions. Neurocomputing 32-33:775-783

Giszter SF Moxon KA Rybak I Chapin JK. (2000) A neurobiological perspective on design of humanoid robots and their components IEEE Intelligent Systems 15(4): 64-69

Giszter S.F. , Davies MR, and Kargo WJ. (2000) Perspective. Augmenting postural primitives in spinal cord: Dynamic force-field structures used in trajectory generation.Ch 25 pp 334-346 In Biomechanics and Neural control of Movement. ed. Winters and Crago. Springer-Verlag.

Giszter SF Grill W Lemay M Mushahwar V and Prochazka A. (2000) Intraspinal microstimulation: techniques, perspectives and prospects for FES in Neural prostheses for restoration of Sensory and motor function ed. KA Moxon and JK Chapin CRC Press.

Giszter, S.F. and Kargo WJ. (2000) Movement organization in the frog spinal cord: Prerational intelligence? pp 323-342 In Pre-rational intelligence: Adaptive Behavior and Intelligent Systems without Symbols and Logic- Volume 1. Ed. H. Cruse, J Dean, and H Ritter. Studies in Cognitive Systems series. Kluwer Academic Press

Giszter SF Moxon KA Rybak I Chapin JK. (2000) Neurobiological and neurorobotic approaches to design of a controller for a humanoid motor system. IEEE /IROS MIT conf on Humanoid robots Proceedings on CD

Gordon-Weeks PR and Fischer I. (2000) MAP1B expression and microtubule stability in growing and regenerating axons. Microscopy Res. and Technique 48:63-74. Abstract.

Grill, W, and MA Lemay (2000) Organized hindlimb motor responses evoked by intraspinal microstimulation," IFESS (International Functional Electrical Stimulation Society) 2000 Conference, Aarlborg, Denmark, June.

Han S, Fischer I. (2000) Neural stem cells and gene therapy: Prospects for repairing the injured spinal cord. JAMA 293, 2300-2301. Abstract.

Himes, BT, and Tessler A. (2000) Neuroprotection from cell death following axotomy. In N.A. Ingoglia and M. Murray (eds.) Nerve Regeneration: New York : Marcel Dekker. pp. 477-504.

Ingoglia, N, Murray M. (Eds). Axonal Regeneration in the Vertebrate CNS. Marcel Dekker. New York, 2000.

Kargo WJ and Giszter SF (2000) Rapid corrections of aimed movements by combination of force-field primitives. J Neurosci 20:409-426. Abstract.

Kargo, WJ and Giszter SF (2000) Afferent roles in hindlimb wiping reflex: free limb kinematics and motor patterns. J Neurophysiology 83(3):1480-1501. Abstract.

MA Lemay, and WM Grill. (2000) Endpoint Force Patterns Evoked by Intraspinal Stimulation - Ipsilateral and Contralateral Responses. Chicago, World Congress on Medical Physics and Biomedical Engineer.

Liu Y, Murray M, Tessler A, Fischer I (2000) Grafting of genetically modified fibrobalsts into the injured spinal cord. In Seil FJ, Ed, Progress in Brain Research, Neural Plasticity and Regeneration. 128:309-322, Elsevier Science. Abstract.

Ma D, Himes T, Shea T, and Fischer I (2000) Axonal transport of microtubule associated protein 1B (MAP1B) in sciatic nerve of adult rats: Distinct transport rates for different isoforms. J. Neurosci. 20:2112-2120. Abstract.

Ma D, Connors T, Nothias F, Fischer I (2000) Regulation of the expression and phosphorylation of MAP1B during regeneration of adult DRG neurons. Neuroscience, 99:157-170. Abstract.

Saavedra RA, Murray M, deLacalle S, Tessler A. (2000) In vivo neuroprotection of injured CNS neurons by a single injection of a DNA plasmid encoding the BCL-2 gene. Progress in Brain Research. In Seil FJ (ed) Progress in Brain Research, Neural Plasticity and Regeneration. 128:365-372. Abstract.

Tobias CA, Kim D, Fischer I (2000) Improved recombinant retroviral titers utilizing trichostatin A BioTechniques, 29:884-89. Abstract.

Chapin , JK, K.A. Moxon, R. S. Markowitz and M.A.L. Nicolelis. (1999) Realtime control of a robot arm using simultaneously recorded neurons in the motor cortex. Nature Neuroscience 2:7. Abstract.

Iwaya, K., K. Mizoi, A. Tessler, and Y. Itoh. (1999) Neurotrophic agents in fibrin glue mediate adult dorsal root regeneration into spinal cord. Neurosurgery 44: 589-596. Abstract.

Kim, D., Y. Adipudi, M. Shibayama, S. Giszter, A. Tessler, M. Murray, and K.J. Simansky. (1999) Direct agonists for serotonin (5-HT2) receptors enhance locomotor function in rats that received neural transplants after neonatal spinal transection. J. Neurosci. 19:6213-6224. Abstract.

Liu Y, Y. Kim, B.T. Himes, S. Chow, M. Murray, A. Tessler, and I. Fischer. (1999) Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons. J. Neurosci. 19:4370-4387. Abstract.

Liu Y, B.T. Himes, J. Solowska-Baird, J. Moul, S. Chow, A. Tessler, E. Snyder and I. Fischer. (1999) Intraspinal delivery of neurotrophin-3 (NT-3) using stem-like cells genetically modified by recombinant retrovirus. Exp. Neurol. 158:9-26. Abstract.

Ma D, S. Chow, M. Obrocka, T. Connors and I. Fischer. (1999) Induction of microtubule-associated protein 1B (MAP1B) expression in Schwann cells during nerve regeneration. Brain Res. 823:141-153. Abstract.

Takahashi, K., E. Schwarz, C. Ljubetic, M. Murray, A. Tessler, and R.A. Saavedra. (1999) A DNA plasmid that codes for human Bcl-2 gene preserves axotomized Clarke's nucleus neurons and reduces atrophy after spinal cord hemisection in adult rats. J. Comp. Neurol.. 404:159-171. Abstract.

Giszter, S.F., W.J. Kargo, M. Davies, and M. Shibayama. (1998) Fetal transplants rescue axial muscle representations in M1 cortex of neonatally transected rats that develop weight support. Journal of Neurophysiology 80:3021-3030. Abstract.

Liu Y, B. T. Himes, J. Moul, S. Chow, H. Jin H, M. Murray, A. Tessler, and I. Fischer. (1998) Intraspinal grafting of fibroblasts genetically modified by recombinant adenoviruses. NeuroReport 9:1075-1079. Abstract.

Shibayama, M., S. Hattori, B.T. Himes, M. Murray, and A. Tessler. (1998) Neurotrophin-3 (NT-3) prevents death of axotomized Clarke's nucleus neurons in adult rat. J. Comp. Neurol. 390:102-111. Abstract.

Shibayama, M., N. Matsui, B.T. Himes, M. Murray, and A. Tessler. (1998) Critical interval for rescue of axotomized neurons by transplants. NeuroReport.9 (1): 1-4. Abstract.

Liu, Y., B.T. Himes, J. Moul, W. Huang, S.Y. Chow, A. Tessler, and I. Fischer. (1997) Application of recombinant adenovirus for in vivo gene delivery to spinal cord. Brain Research 768: 19-29. Abstract.

Miya, D., S. Giszter, F. Mori, V. Adipudi, A. Tessler, and M. Murray. (1997) Fetal transplants alter the development of function after spinal cord transection in newborn rats. J. Neuroscience 17 (12): 4856-4872. Abstract.

Mori, F., B.T. Himes, M. Kowada, M. Murray, and A. Tessler. (1997) Fetal spinal cord transplants rescue some axotomized rubrospinal neurons from retrograde cell death in adult rats. Exp. Neurol. 143:45-60. Abstract.

Ditunno, J.F., Graziani, V., and A. Tessler. (1996) Neurological assessment in spinal cord injury. In: F. Seil (ed.): Neuronal Regeneration, Reorganization and Repair. New York:Raven Press. pp. 325-333. Abstract.

Tessler, A., S.F. Giszter, B.T. Himes, M. Murray, and I. Fischer. (1996) Embryonic spinal cord transplants enhance locomotor performance in spinalized newborn rats. In F.J. Seil (ed.) Neuronal Regeneration, Reorganization and Repair: New York: Raven Press. pp. 291-303. Abstract.

Tessler, A. and M. Murray. (1996) Neural transplantation: spinal cord. In R.P. Lanza and W.L. Chick (eds.) Yearbook of Cell and Tissue Transplantation. 1996/1997, 175-182.

« Core Facilities | Funding »



Home \| Faculty \| Research \| Postdocs \| Residents \| Students \| Seminars \| Education \| Fellowships \| Resources
Spinal Cord Research Center \| Cellular Neurobiology \| Systems Neurobiology \| Computer Vision \| Neuroengineering \| Bone Biology